Serological Assay and Genotyping of Hepatitis C Virus in Infected Patients in Zanjan Province

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Serological Assay and Genotyping of Hepatitis C Virus in Infected Patients in Zanjan Province

BACKGROUND Hepatitis C Virus (HCV), a public health problem, is an enveloped, single-stranded RNA virus and a member of the Hepacivirus genus of the Flaviviridae family. Liver cancer, cirrhosis, and end-stage liver are the outcomes of chronic infection with HCV. HCV isolates show significant heterogeneity in genetics around the world. Therefore, determining HCV genotypes is a vital step in dete...

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serological assay and genotyping of hepatitis c virus in infected patients in zanjan province

conclusions according to the results, it was found that hcv high prevalent genotype in zanjan is subtype 3a. analysis of the results provides identification of certain hcv genotypes, and these valuable findings could affect the type and duration of the treatment. results samples indicated 216 bp bands on 2% agarose gel. analyses of the results demonstrated that the most dominant subtype was 3a ...

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Detection of SENV Virus in Healthy, Hepatitis B- and Hepatitis C-Infected Individuals in Yazd Province, Iran

Background: SEN virus (SENV) is the latest virus proposed as a cause of unknown hepatitis cases. Among nine detected genotypes of the virus, genotypes D and H are more frequent in hepatitis cases of unknown origin. The aim of this study was to determine the frequency of SENV-D and SENV-H genotypes in the sera of healthy individuals and hepatitis B and C patients. Methods: Totally, 200 serum sam...

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Molecular Assay and Genotyping of Hepatitis C Virus among Infected Egyptian and Saudi Arabian Patients

Hepatitis C virus (HCV) infection is a major health problem recognized globally. HCV is a common cause of liver fibrosis that may lead to liver cirrhosis or hepatocellular carcinoma. The aim of this study was to estimate the prevalence of HCV infection and genotyping among Egyptian and Saudi Arabian chronic patients using different molecular techniques. HCV RNA viral load was assessed by real-t...

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Hepatitis C Virus Genotyping in Chronic Hepatitis C Patients

Chronic hepatitis C virus infection is a massive worldwide healthcare burden with estimated costs in the USA alone of over $5 billon per annum. The virus has a 9.5kb positive sense single-stranded RNA genome with striking heterogeneity between isolates, which has led to it being divided into 6 genotypes and more than 50 subtypes and many quasispecies that has been arisen due to the infidelity o...

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ژورنال

عنوان ژورنال: Hepatitis Monthly

سال: 2014

ISSN: 1735-143X,1735-3408

DOI: 10.5812/hepatmon.17323